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cyclosporine will increase the stage or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.lenacapavir will improve the amount or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.primidone will decrease the level or influence of bortezomib by